MadeMed Review: A Named 9 mg Vial, and a $537 Way In

The short version

MadeMed sells compounded sermorelin as a named 9 mg/3 mL vial at $179 a month — billed $537 every three months, because it sells no one-month plan at all. Open the product page and the option already selected for you is the other one: six months at $169 a month, billed $1,014 up front. The monthly figure in the headline is not a number you can pay. Entry cost is.

That is the criticism. The reason to keep reading is the strength printed beside it. MadeMed tells you the vial is 9 mg in 3 mL, which lets you work out what a milligram of sermorelin costs you here. Most of our ranking does not give you that. It also requires a baseline IGF-1 blood test before it will prescribe — one of only four providers we track that refuse to write a prescription without a lab — names the corporation behind the brand, names a dispensing pharmacy in its Terms, and publishes the forty states it serves with the ten it does not serve listed by name.

So: a better-documented company than its price presentation suggests, sold behind a commitment a first-time buyer should weigh before clicking.

MadeMed pays us if you sign up through this site — see our disclosure. It softened nothing below.

The price, read off the page

Read from the injectable sermorelin page on 29 August 2026, both panels clicked open:

• •Quarterly — "$179 /month. Sermorelin 9mg/3mL daily injection (30-day supply) shipped monthly. Billed $537 every 3 months."
• •Six months — "$169 /month… Billed $1014 every 6 months." Flagged "Most Popular" and "Save $10/mo", and pre-selected when the page loads.

The sublingual tablet runs on the same two rungs: 1000 mcg at $109 a month billed $327 quarterly, or $99 a month billed $594 for six.

Two things follow. First, the arithmetic is honest — unlike a twelve-week cycle, "every 3 months" really does recur four times a year, so $179 a month really is $2,148 a year and the six-month rung $2,028. Second, there is no rung below the quarter. Every plan on the page is a prepayment, and the smaller of the two prepayments is $537.

MadeMed gives a reason for it, which is more than most three-month minimums get. Its own FAQ says initial changes appear at two to four weeks but "the full therapeutic benefits of Sermorelin require 8-12 weeks of consistent treatment. This is why we recommend a minimum 3-month commitment." Read against the evidence, that is a defensible clinical position rather than a retention tactic. It is still $537.

The plan auto-renews. The Terms say you are "charged on a recurring basis (e.g., every 30 or 90 days) until you cancel", that cancellations "will be effective at the end of the current billing period", and — the sentence that matters most — "We do not offer prorated refunds." Canceling in month two of a quarter you have already paid for returns nothing.

What a milligram costs, which is the only comparison worth making

A monthly price for a compounded peptide is close to meaningless on its own. Two companies can charge the same $180 and ship quantities that differ by a factor of two, because what is priced is a compounded vial, not a standard pack. The figure only becomes comparable once you know the milligrams behind it — and most sellers decline to print them.

Four providers on our ranking publish both a strength and a monthly price for injectable sermorelin: MadeMed, Try Ageless, Brightmeds and Care Bare Rx. Here is what their months buy.

MadeMed is the most expensive of the four per milligram — just under $20 a milligram on the quarterly plan, against $12.60 at Try Ageless, $13.07 at Brightmeds and a flat $15.00 at Care Bare Rx. The specificity that makes MadeMed worth praising is the same specificity that shows it charging a premium.

Two honest caveats before you treat that as settled. A larger vial is only worth more if your prescription actually uses it, and MadeMed's own FAQ says the price is not fixed to the vial anyway: "If your doctor adjusts your dose based on your response, we'll adjust your price accordingly." None of the other three promises the reverse either. And Try Ageless's $189 is itself a discount off a $239 list price, so the gap narrows if that promotion ends.

The dose its two pages disagree about

Publishing more numbers means more of them can be checked against each other, and two of MadeMed's do not reconcile.

The injectable page sells a 9 mg/3 mL vial and describes it as a 30-day supply, injected daily. The sublingual page opens a FAQ headed "Why is the oral dose (1000mcg) higher than the injectable (900mcg)?", and answers it by explaining that a sublingual tablet is dosed higher to deliver "a clinically equivalent amount of bioavailable Sermorelin to the 900mcg injectable".

Nine hundred micrograms a day for thirty days is 27 milligrams. The vial holds nine. Those two pages cannot both be describing the same month of treatment.

We are not going to guess which is right, and you should not either — the dose is set by the prescriber, not by a shopping page, and MadeMed says so plainly when asked: "Your specific dosage will be determined by your provider based on your medical history and goals." But anyone comparing sermorelin on milligrams should ask which number governs before the $537 leaves the account. Our dosing evidence page covers what the published trials actually used.

Who compounds it, who prescribes it, and where it ships

The corporate structure is disclosed. The Terms name IDL Health LLC, trading as MadeMed, at a Houston, Texas address, and state that clinical care is delivered by Xpedicare, LLC, "solely responsible for providing clinical services and making all medical decisions", whose providers are "not contracted or employed by MadeMed".

A pharmacy is named, twice, and it is not the one on the About page. The Terms name AbsoluteRx as "the Pharmacy", and the Privacy Policy repeats it. Separately, /about says the company partners "exclusively with licensed, accredited compounding pharmacies in the United States, like our partners at Red Rock Pharmacy". Naming any pharmacy at all puts MadeMed ahead of most of this ranking. Two qualifiers: which one fills a sermorelin order is not stated, and Red Rock also dispenses for Brightmeds, so this describes the network rather than something exclusive to MadeMed.

No 503A or 503B classification is claimed anywhere. The word appears on none of the pages we read on 29 August 2026 — not on either sermorelin page, not in the Terms or Privacy Policy, not on the About or How It Works pages. That distinction is what separates a state-licensed compounding pharmacy from an FDA-registered outsourcing facility⁶, and MadeMed leaves it out. To its credit it does not blur the line either: the Terms state that "Compounded drugs are not approved by the Food and Drug Administration (FDA) and are not evaluated for safety or efficacy", and the product page repeats it.

One physician is named; you cannot check him. /about and /how-it-works both say the medical team is "led by board-certified physicians including Dr. Thai Pham, a Brown University-educated internist with over 25 years of clinical experience." No license number, no NPI and no state is published for him, and more than one clinician of that name appears in the national provider registry, so the credential is a claim rather than something a reader can verify. The only individual documented in depth is its Chief Medical Reviewer, Dr Christine Folake Coon, PharmD, a Texas-registered pharmacist who vets the site's editorial content — a content role, not a prescribing one.

Forty states, with the exclusions named. The sermorelin FAQ says treatment is offered in 40 states and lists the ten it is not: Alabama, Alaska, Arkansas, Hawaii, Massachusetts, Missouri, New Mexico, New York, South Carolina and Virginia. The 40-state list on /about matches it exactly. Naming the gaps beats claiming "most states".

Refunds, billing and the lab you also have to pay for

If a physician declines to prescribe, the product FAQ says: "we'll refund your payment minus the $39 consultation fee. This fee covers the cost of the physician's time." Elsewhere the same $39 is described as a quarterly charge folded into the monthly price rather than billed separately. So a declined application costs $39 and returns the rest — clearer than a silent forfeit, less generous than the full refunds a few providers here promise.

After that, the returns picture is strict, and stated strictly: "all sales of both prescription and over-the-counter products are final and non-refundable", and consultation fees are "non-refundable after the consultation has been completed". Damaged, incorrect or lost orders are replaced or refunded if you report them within seven days. The returns page, unchanged since 1 November 2025, does not mention the declined-prescription refund at all, so that promise lives only in the product FAQ.

The billing conduct is good: "We email you 7 days before every charge with the exact amount and easy options to pause, skip, or cancel", and cancellation is "one click from your dashboard." Pausing is said to stop billing immediately. None of that gives back money already taken for a quarter in progress.

One cost is missing from every figure above. MadeMed will not prescribe injectable sermorelin without a baseline IGF-1 test, taken at Labcorp or Quest or uploaded from the last six months. Requiring it is right — IGF-1 is the standard readout for whether a GHRH analog is doing anything³, and our lab monitoring guide recommends one whoever you buy from. But the lab is not included in the plan and is priced nowhere on the site, so the true cost of starting is $537 plus an amount MadeMed does not tell you.

Does the treatment justify prepaying for it?

Sermorelin is a synthetic copy of the first 29 amino acids of growth-hormone-releasing hormone. It does not supply growth hormone; it prompts your own pituitary to release more of it³, which is why it is dosed at night and why the best-supported effects sit on sleep and the GH/IGF-1 axis rather than on the mirror. Nightly GHRH(1-29) raised GH and IGF-1 in healthy older men in a controlled study⁴, while the broader literature on raising growth hormone in healthy adults reports small body-composition changes, no functional gain and a measurable side-effect rate⁵. Our evidence review grades each claim, and the side-effect page covers what to expect.

The sublingual tablet needs its own flag. MadeMed's account of why 1000 mcg sublingual matches 900 mcg injected describes mucosal absorption fairly, but peptides of this size cross the oral mucosa poorly and unpredictably, and the equivalence is asserted rather than referenced⁷. Our sublingual page sets out what is established.

All of which argues for finding out cheaply first, and a $537 opening charge is the opposite of cheap. That is the tension at the center of this company.

Verdict

MadeMed is a well-documented seller with an awkward front door. It names its vial, its corporation, its clinical group, a pharmacy, its states and its exclusions; it requires a lab most competitors skip; it warns you seven days before every charge and lets you cancel in one click. Set against that: no monthly plan exists, the cheapest entry is $537, the six-month option at $1,014 is the one pre-selected for you, canceling mid-term refunds nothing, the required IGF-1 lab is unpriced, and the 9 mg vial costs more per milligram than any other strength published on this site.

Buy it if you have already decided sermorelin is worth three months and you want a company that will tell you what is in the syringe. If you are still deciding, our price-sorted list shows who sells a single month, and what they charge for one.