He & She MD Review: $149 a Month Means Buying a Year

The short version

He & She MD sells sermorelin injections from $149 a month — but only if you buy twelve months at once. Month to month is $229, with $179 on three months and $159 on six. The company publishes all four rungs; what it advertises, in the headline on its own sermorelin page, is the cheapest one, with the term in an asterisked footnote underneath.

That is worth being precise about rather than annoyed by, because the ladder itself is honest work: every rung is a monthly figure you can compare, medication, supplies, shipping and provider support are stated as inside it, and there is no membership fee stacked on top. It also names the pharmacies that dispense and the physicians who prescribe, which most of the sellers on our sermorelin ranking will not do. Read the price as $229 unless you are willing to pay about $1,788 up front, and this is a reasonable place to buy.

What it actually costs

The hero says "Starting at $149 /month*" with "Same price at every dose", and the asterisk resolves to "Price for purchase of 12 months supply." The full table sits a little further down the page, under "How much does treatment cost?" — the company's own words are that "pricing is based on your plan length, with longer plans offering lower monthly pricing":

Three things follow from that table.

"Same price at every dose" is a dose claim, not a price guarantee. It means your monthly cost does not climb if the clinician raises your dose — genuinely useful, since dose escalation is where several competitors quietly add money. It does not mean one price. The price moves with the term, from $149 to $229, a spread of about 54%.

The advertised rung is the one that costs the most to enter. Twelve months at $149 is $1,788 committed before you know whether sermorelin does anything for you. Our own read of the evidence is that the sleep and IGF-1 signals are the better-supported ones and the body-composition claims are weaker³⁵, which is an argument for starting on the rung you can leave.

Everything is inside the number. Medication, supplies, shipping and provider support, "if prescribed" — no membership fee, no insurance, and the site says nothing is billed unless a clinician writes the prescription. That is what makes $229 comparable with the other month-to-month figures on this site rather than a headline with fees hiding behind it.

The rest of the longevity shelf is priced the same way: NAD+ as an injection, nasal spray or cream at $149 a month, sermorelin at $149, lipotropic MIC + B12 at $109 — every one of them footnoted to a twelve-month purchase — and glutathione at $100 on a three-month footnote.

Who fills the prescription

This is where He & She MD does better than most, and where its own FAQ leaves one question open.

It names F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield, OH 45014, (877) 858-3784 — a street address and a phone number, which is more than the majority of compounded-peptide sellers publish. It also names a second dispenser, Specialty Medical Drugstore LLC, doing business as GoGoMeds, and says it will "continue to partner with both" for fulfillment.

The open question is which one fills a sermorelin injection, because the FAQ says of Jungle Jim's that it "maintains a license in 44 US states" and that "they cannot dispense sterile compounds", listing ten states it is not licensed in: California, Nevada, New Jersey, North Carolina, Texas, Massachusetts, Mississippi, New Hampshire, West Virginia and Delaware. Sermorelin is a sterile injectable. So the pharmacy the site describes in the most detail is, by its own account, not the one that can send you this product, and the site does not say that GoGoMeds is — it simply lists both. Ask which pharmacy your order goes to.

Two more qualifiers. No compounding classification appears anywhere — neither "503A" nor "503B" is on the sermorelin page, the longevity menu, the FAQ or the homepage as of 29 August 2026. And Jungle Jim's is a facility other telehealth storefronts also name, so it tells you who dispenses rather than anything exclusive to this clinic. What the FAQ does say is that state boards inspect its pharmacies every six to twelve months and that sterile compound batches undergo third-party testing.

Who prescribes

Wasef Health, PC, c/o Michael Wasef MD is named as the clinical provider, with an email address and an office address in Pinellas Park, Florida. Dr. Ozita Cooper, MD, dual board-certified in obesity and emergency medicine, is named as chief medical officer on the homepage. Naming both the practice and the officer is unusual in this category and it is the strongest single thing about the company: if something goes wrong you know who to ask.

One detail cuts against it. The clinical address published in the FAQ is a PO Box, on a site whose own shipping policy says it will not ship to PO Boxes.

Where the site argues with itself

A marketing block that appears across the site, the sermorelin page included, advertises "FDA-regulated pharmacies." The FAQ answering the same question is more careful and says "FDA-registered pharmacies." Those are different claims. Registration means a facility has filed with the agency; it is not the FDA regulating, inspecting or approving what comes out of it. The homepage's own fine print, scoped to the GLP-1 line, says it plainly: medications are "produced in USP-compliant, state-regulated pharmacies but not reviewed by the FDA for safety, efficacy, or quality." The careful sentence is the true one, and it is the one in the smallest type.

Compounded sermorelin is not an FDA-approved product, and no compounded drug is reviewed for safety or efficacy before it is dispensed⁴. That is true of every seller on this ranking, including the ones we are paid by. It is worth naming here only because this site publishes both versions of the claim on the same page.

Does the product justify a year up front?

Sermorelin is a synthetic copy of the first 29 amino acids of growth-hormone-releasing hormone. Rather than supplying growth hormone, it prompts the pituitary to release more of your own², which is why it is dosed at night and why the evidence that holds up best is about sleep and the GH/IGF-1 axis rather than about looking different in the mirror. Nightly GHRH(1-29) in healthy older men raised GH and IGF-1 in a controlled study³; the broader literature on augmenting growth hormone in healthy adults finds small body-composition changes, no functional gain, and a real side-effect rate⁵. Our evidence review grades it that way in full.

Nothing about that says buy the annual plan. If you want to know whether it works for you, the $229 rung answers the question for about two and a half months of what the twelve-month rung costs to start.

Verdict

Buy the month-to-month plan. He & She MD publishes a complete ladder, names its pharmacies and its prescribers, includes supplies and shipping in the price, and does not require labs or insurance — that is a solid, checkable offer, and at $229 it sits mid-table on our price-sorted list rather than at the cheap end. The $149 headline is real but it is a twelve-month commitment to a peptide whose best-supported effect is on your sleep, and you will know within a couple of months whether you are getting it. Before you order, ask which of the two named pharmacies fills the injection.